Ontology highlight
ABSTRACT:
SUBMITTER: Attner MA
PROVIDER: S-EPMC3418307 | biostudies-other | 2012 Aug
REPOSITORIES: biostudies-other
Molecular biology of the cell 20120620 16
The mitotic exit network (MEN) is an essential GTPase signaling pathway that triggers exit from mitosis in budding yeast. We show here that during meiosis, the MEN is dispensable for exit from meiosis I but contributes to the timely exit from meiosis II. Consistent with a role for the MEN during meiosis II, we find that the signaling pathway is active only during meiosis II. Our analysis further shows that MEN signaling is modulated during meiosis in several key ways. Whereas binding of MEN comp ...[more]