Subversion of cell signaling by pathogens.
Ontology highlight
ABSTRACT:
SUBMITTER: Alto NM
PROVIDER: S-EPMC3428769 | biostudies-other | 2012 Sep
REPOSITORIES: biostudies-other
Publications
Subversion of cell signaling by pathogens.
Cold Spring Harbor perspectives in biology 20120901 9
Pathogens exploit several eukaryotic signaling pathways during an infection. They have evolved specific effectors and toxins to hijack host cell machinery for their own benefit. Signaling molecules are preferentially targeted by pathogens because they globally regulate many cellular processes. Both viruses and bacteria manipulate and control pathways that regulate host cell survival and shape, including MAPK signaling, G-protein signaling, signals controlling cytoskeletal dynamics, and innate im ...[more]
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