Ontology highlight
ABSTRACT:
SUBMITTER: Jansen G
PROVIDER: S-EPMC3434782 | biostudies-other | 2012 Sep
REPOSITORIES: biostudies-other
Jansen Gregor G Määttänen Pekka P Denisov Alexey Y AY Scarffe Leslie L Schade Babette B Balghi Haouaria H Dejgaard Kurt K Chen Leanna Y LY Muller William J WJ Gehring Kalle K Thomas David Y DY
Molecular & cellular proteomics : MCP 20120604 9
Chaperones and foldases in the endoplasmic reticulum (ER) ensure correct protein folding. Extensive protein-protein interaction maps have defined the organization and function of many cellular complexes, but ER complexes are under-represented. Consequently, chaperone and foldase networks in the ER are largely uncharacterized. Using complementary ER-specific methods, we have mapped interactions between ER-lumenal chaperones and foldases and describe their organization in multiprotein complexes. W ...[more]