Ontology highlight
ABSTRACT:
SUBMITTER: Inoue K
PROVIDER: S-EPMC3457844 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Inoue Kentaro K Maeda Kazuhiro K Kato Yuki Y Tonami Shinpei S Takagi Shogo S Kurata Hiroyuki H
Source code for biology and medicine 20120828 1
Computer simulation has been an important technique to capture the dynamics of biochemical networks. In most networks, however, few kinetic parameters have been measured in vivo because of experimental complexity. We develop a kinetic parameter estimation system, named the CADLIVE Optimizer, which comprises genetic algorithms-based solvers with a graphical user interface. This optimizer is integrated into the CADLIVE Dynamic Simulator to attain efficient simulation for dynamic models. ...[more]