Unknown

Dataset Information

0

Rates of fatty acid oxidations by P450 compound I are pH dependent.

ABSTRACT: The rates of oxidation of fatty acids by CYP119 compound I were dependent on the pH of the medium. The plot shows log k values for reactions of acids as a function of pH, where the slopes indicate mixed third-order and fourth-order dependence on base concentration. For palmitic acid, the rate increased 50-fold over the pH range 6.8-7.3.

SUBMITTER: Su Z 

PROVIDER: S-EPMC3477493 | biostudies-other | 2012 Sep

REPOSITORIES: biostudies-other

Json Xml
altmetric image

Publications

Rates of fatty acid oxidations by P450 compound I are pH dependent.

Su Zhi Z   Horner John H JH   Newcomb Martin M  

Chembiochem : a European journal of chemical biology 20120813 14

The rates of oxidation of fatty acids by CYP119 compound I were dependent on the pH of the medium. The plot shows log k values for reactions of acids as a function of pH, where the slopes indicate mixed third-order and fourth-order dependence on base concentration. For palmitic acid, the rate increased 50-fold over the pH range 6.8-7.3. ...[more]