Ontology highlight
ABSTRACT:
SUBMITTER: Chu D
PROVIDER: S-EPMC3488257 | biostudies-other | 2012 Nov
REPOSITORIES: biostudies-other
Chu Dominique D von der Haar Tobias T
Nucleic acids research 20120910 20
Translation in baker's yeast involves the coordinated interaction of 200,000 ribosomes, 3,000,000 tRNAs and between 15,000 and 60,000 mRNAs. It is currently unknown whether this specific constellation of components has particular relevance for the requirements of the yeast proteome, or whether this is simply a frozen accident. Our study uses a computational simulation model of the genome-wide translational apparatus of yeast to explore quantitatively which combinations of mRNAs, ribosomes and tR ...[more]