Unknown

Dataset Information

0

Preferred antiretroviral drugs for the next decade of scale up.


ABSTRACT: Global commitments aim to provide antiretroviral therapy (ART) to 15 million people living with HIV by 2015, and recent studies have demonstrated the potential for widespread ART to prevent HIV transmission. Increasingly, countries are adapting their national guidelines to start ART earlier, for both clinical and preventive benefits. To maximize the benefits of ART in resource-limited settings, six key principles need to guide ART choice: simplicity, tolerability and safety, durability, universal applicability, affordability and heat stability. Currently available drugs, combined with those in late-stage clinical development, hold great promise to simplify treatment in the short term. Over the longer-term, newer technologies, such as long-acting formulations and nanotechnology, could radically alter the treatment paradigm. This commentary reviews recommendations made in an expert consultation on treatment scale up in resource-limited settings.

SUBMITTER: Andrieux-Meyer I 

PROVIDER: S-EPMC3494169 | biostudies-other | 2012 Sep

REPOSITORIES: biostudies-other

altmetric image

Publications

Preferred antiretroviral drugs for the next decade of scale up.

Andrieux-Meyer Isabelle I   Calmy Alexandra A   Cahn Pedro P   Clayden Polly P   Raguin Gilles G   Katlama Christine C   Vitoria Marco M   Levin Andrew A   Lynch Sharonann S   Goemaere Eric E   Ford Nathan N  

Journal of the International AIDS Society 20120918 2


Global commitments aim to provide antiretroviral therapy (ART) to 15 million people living with HIV by 2015, and recent studies have demonstrated the potential for widespread ART to prevent HIV transmission. Increasingly, countries are adapting their national guidelines to start ART earlier, for both clinical and preventive benefits. To maximize the benefits of ART in resource-limited settings, six key principles need to guide ART choice: simplicity, tolerability and safety, durability, universa  ...[more]

Similar Datasets

| S-EPMC5925449 | biostudies-other
| S-EPMC4740352 | biostudies-other
| S-EPMC5927327 | biostudies-other
2021-12-29 | GSE188210 | GEO
| S-EPMC5540587 | biostudies-literature
| S-EPMC2895748 | biostudies-other
| S-EPMC4827556 | biostudies-other
| S-EPMC3775764 | biostudies-literature
| S-EPMC5822883 | biostudies-other
| S-EPMC5456062 | biostudies-literature