Multifocality and multicentricity in breast cancer and survival outcomes.
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ABSTRACT:
SUBMITTER: Lynch SP
PROVIDER: S-EPMC3501230 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
Publications
Multifocality and multicentricity in breast cancer and survival outcomes.
Lynch S P SP Lei X X Chavez-MacGregor M M Hsu L L Meric-Bernstam F F Buchholz T A TA Zhang A A Hortobagyi G N GN Valero V V Gonzalez-Angulo A M AM
Annals of oncology : official journal of the European Society for Medical Oncology 20120709 12
<h4>Background</h4>The clinicopathological characteristics and the prognostic significance of multifocal (MF) and multicentric (MC) breast cancers are not well established.<h4>Patients and methods</h4>MF and MC were defined as more than one lesion in the same quadrant or in separate quadrants, respectively. The Kaplan-Meier product limit was used to calculate recurrence-free survival (RFS), breast cancer-specific survival (BCSS), and overall survival (OS). Cox proportional hazards models were fi ...[more]
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