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Molecular logic gates for DNA analysis: detection of rifampin resistance in M. tuberculosis DNA.

ABSTRACT: Elementary, Dr. Watson! A combination of YES and OR logic gates was applied to differentiate between DNA sequences of wild-type and rifampin-resistant (Rif(r)) Mycobacterium tuberculosis (Mtb) in a multiplex real-time fluorescent assay.

SUBMITTER: Cornett EM 

PROVIDER: S-EPMC3517149 | biostudies-other | 2012 Sep

REPOSITORIES: biostudies-other

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Molecular logic gates for DNA analysis: detection of rifampin resistance in M. tuberculosis DNA.

Cornett Evan M EM   Campbell Eleanor A EA   Gulenay George G   Peterson Evan E   Bhaskar Neha N   Kolpashchikov Dmitry M DM  

Angewandte Chemie (International ed. in English) 20120809 36

Elementary, Dr. Watson! A combination of YES and OR logic gates was applied to differentiate between DNA sequences of wild-type and rifampin-resistant (Rif(r)) Mycobacterium tuberculosis (Mtb) in a multiplex real-time fluorescent assay. ...[more]

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