Mechanism for adaptive remodeling of the bacterial flagellar switch.
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ABSTRACT:
SUBMITTER: Lele PP
PROVIDER: S-EPMC3523824 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
Publications
Mechanism for adaptive remodeling of the bacterial flagellar switch.
Lele Pushkar P PP Branch Richard W RW Nathan Vedhavalli S J VS Berg Howard C HC
Proceedings of the National Academy of Sciences of the United States of America 20121119 49
The bacterial flagellar motor has been shown in previous work to adapt to changes in the steady-state concentration of the chemotaxis signaling molecule, CheY-P, by changing the FliM content. We show here that the number of FliM molecules in the motor and the fraction of FliM molecules that exchange depend on the direction of flagellar rotation, not on CheY-P binding per se. Our results are consistent with a model in which the structural differences associated with the direction of rotation modu ...[more]
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