Ontology highlight
ABSTRACT:
SUBMITTER: Thakur A
PROVIDER: S-EPMC3533807 | biostudies-other | 2012 Jun
REPOSITORIES: biostudies-other
Thakur Ajit A Fitzpatrick Scott S Zaman Abeyat A Kugathasan Kapilan K Muirhead Ben B Hortelano Gonzalo G Sheardown Heather H
Journal of biological engineering 20120611 1
Controlling gene expression via small interfering RNA (siRNA) has opened the doors to a plethora of therapeutic possibilities, with many currently in the pipelines of drug development for various ocular diseases. Despite the potential of siRNA technologies, barriers to intracellular delivery significantly limit their clinical efficacy. However, recent progress in the field of drug delivery strongly suggests that targeted manipulation of gene expression via siRNA delivered through nanocarriers ca ...[more]