Ontology highlight
ABSTRACT:
SUBMITTER: Hass B
PROVIDER: S-EPMC3554503 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
Hass Bastian B Pooley Jayne J Harrington Adrian E AE Clemens Andreas A Feuring Martin M
Thrombosis journal 20121231 1
Effective treatment of venous thromboembolism (VTE) strikes a balance between prevention of recurrence and bleeding complications. The current standard of care is heparin followed by a vitamin K antagonist such as warfarin. However, this option is not without its limitations, as the anticoagulant effect of warfarin is associated with high inter- and intra-patient variability and patients must be regularly monitored to ensure that anticoagulation is within the narrow target therapeutic range. Sev ...[more]