Ontology highlight
ABSTRACT:
SUBMITTER: Kurimoto E
PROVIDER: S-EPMC3564829 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Kurimoto Etsuko E Miyahara Nobuaki N Kanehiro Arihiko A Waseda Koichi K Taniguchi Akihiko A Ikeda Genyo G Koga Hikari H Nishimori Hisakazu H Tanimoto Yasushi Y Kataoka Mikio M Iwakura Yoichiro Y Gelfand Erwin W EW Tanimoto Mitsune M
Respiratory research 20130120
<h4>Background</h4>Pulmonary emphysema is characterized by alveolar destruction and persistent inflammation of the airways. Although IL-17A contributes to many chronic inflammatory diseases, it's role in the inflammatory response of elastase-induced emphysema remains unclear.<h4>Methods</h4>In a model of elastase-induced pulmonary emphysema we examined the response of IL-17A-deficient mice, monitoring airway inflammation, static compliance, lung histology and levels of neutrophil-related chemoki ...[more]