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4-[5-(4-Chloro-phen-yl)-3-methyl-1H-pyrazol-1-yl]benzene-sulfonamide.

ABSTRACT: In the title compound, C(16)H(14)ClN(3)O(2)S, the dihedral angle between the benzene and pyrazole rings is 52.75?(2)°, while that between the pyrazole and 4-chloro-phenyl rings is 54.0?(3)°. The terminal sulfonamide group adopts an approximately tetra-hedral geometry about the S atom with a C-S-N angle of 108.33?(10)°. In the crystal, pairs of N-H?N hydrogen bonds lead to the formation of inversion dimers. These dimers are linked via a second pair of N-H?N hydrogen bonds and C-H?O interactions, forming a two-dimensional network lying parallel to the bc plane. The two-dimensional networks are linked via C-H?Cl interactions, forming a three-dimensional structure.

SUBMITTER: Farrukh MA

PROVIDER: S-EPMC3569817 | biostudies-other | 2013 Feb

REPOSITORIES: biostudies-other

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4-[5-(4-Chloro-phen-yl)-3-methyl-1H-pyrazol-1-yl]benzene-sulfonamide.

Farrukh Muhammad A MA Mohamed Shaaban K SK Ahmed Maqsood M Marzouk Adel A AA El-Moghazy Samir M SM

Acta crystallographica. Section E, Structure reports online 20130126 Pt 2

In the title compound, C(16)H(14)ClN(3)O(2)S, the dihedral angle between the benzene and pyrazole rings is 52.75 (2)°, while that between the pyrazole and 4-chloro-phenyl rings is 54.0 (3)°. The terminal sulfonamide group adopts an approximately tetra-hedral geometry about the S atom with a C-S-N angle of 108.33 (10)°. In the crystal, pairs of N-H⋯N hydrogen bonds lead to the formation of inversion dimers. These dimers are linked via a second pair of N-H⋯N hydrogen bonds and C-H⋯O interactions, ...[more]

PMID: 23424563

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4-Chloro-N-(3-methyl-phen-yl)benzene-sulfonamide.

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Project description:With respect to the planar five-membered ring of the title compound, C(16)H(15)N(3)O(2)S, the phenyl ring is aligned at 47.0?(1)° and the phenyl-ene ring at 37.6?(1)°. The amino group has the N atom in a pyramidal geometry; the group is a hydrogen-bond donor to the sulfonyl O atom of one mol-ecule and to the pyrazole N atom of another mol-ecule, resulting in the formation of a layer parallel to the bc plane.

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4-Chloro-2-methyl-N-(3-methyl-phen-yl)benzene-sulfonamide.

Project description:The N-H bond in the title compound, C(14)H(14)ClNO(2)S, the dihedral angle between the two benzene rings is 75.5?(1)°. The crystal structure features inversion-related dimers linked by pairs of N-H?O hydrogen bonds.

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4-Chloro-2-methyl-N-(4-methyl-phen-yl)benzene-sulfonamide.

Project description:The asymmetric unit of the title compound, C(14)H(14)ClNO(2)S, contains two independent mol-ecules. The torsion angles of the C-SO(2)-NH-C segments in the two mol-ecules are -76.5 (5) and -48.3 (4)°. The two aromatic rings are tilted relative to each other by 76.6 (2)° in one mol-ecule and 70.7 (2)° in the other. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers.

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4-Chloro-2-methyl-N-(2-methyl-phen-yl)-benzene-sulfonamide.

Project description:In the crystal structure of the title compound, C(14)H(14)ClNO(2)S, the two aromatic rings are tilted relative to each other by 45.8 (1)°. In the crystal, inversion dimers linked by pairs of N-H⋯O hydrogen bonds occur.

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Project description:In the title compound, C(14)H(10)F(3)N(3)O(3)S, there are significant twists in the mol-ecule, as seen in the values of the dihedral angles between the pyrazole ring and each of the furan [31.1?(2)°] and benzene rings [55.58?(10)°]. The amino N atom occupies a position almost normal to the benzene ring [N-S-C(ar)-C(ar) (ar = aromatic) torsion angle = 83.70?(19)°]. One amino H atom forms a hydrogen bond to the tricoordinate pyrazole N atom and the other inter-acts with a sulfonamide O atom, forming a supra-molecular chain along [010]. The chains are consolidated into a supra-molecular layers via C-H?O inter-actions involving the second sulfonamide O atom; layers stack along [10-1]. The furan ring was found to be disordered over two diagonally opposite orientations of equal occupancy.

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