Ontology highlight
ABSTRACT:
SUBMITTER: Highnam G
PROVIDER: S-EPMC3592458 | biostudies-other | 2013 Jan
REPOSITORIES: biostudies-other
Nucleic acids research 20121022 1
Repetitive sequences are biologically and clinically important because they can influence traits and disease, but repeats are challenging to analyse using short-read sequencing technology. We present a tool for genotyping microsatellite repeats called RepeatSeq, which uses Bayesian model selection guided by an empirically derived error model that incorporates sequence and read properties. Next, we apply RepeatSeq to high-coverage genomes from the 1000 Genomes Project to evaluate performance and ...[more]