Ontology highlight
ABSTRACT:
SUBMITTER: Eckert WA
PROVIDER: S-EPMC359919 | biostudies-other | 1991 Apr
REPOSITORIES: biostudies-other
Eckert W A WA Plass C C Weith A A Traut W W Winking H H
Molecular and cellular biology 19910401 4
Several populations of the house mouse, Mus musculus, are polymorphic for the presence or absence of an inherited homogeneously staining region (HSR) in chromosome 1. The HSR consists of highly amplified DNA sequences, present in low copy numbers in the HSR- genome. A cloned HSR-derived genomic sequence detected transcripts of about 1.3 and 4.5 kb on blots of poly(A)+ RNA from liver of HSR+ mice but not from that of HSR- mice. A cDNA library was established from RNA of HSR+ mice and screened wit ...[more]