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Vocal fold vibration measurements using laser Doppler vibrometry.

ABSTRACT: The objective of this study was to measure the velocity of the superior surface of human vocal folds during phonation using laser Doppler vibrometry (LDV). A custom-made endoscopic laser beam deflection unit was designed and fabricated. An in vivo clinical experimental procedure was developed to simultaneously collect LDV velocity and video from videolaryngoscopy. The velocity along the direction of the laser beam, i.e., the inferior-superior direction, was captured. The velocity was synchronous with electroglottograph and sound level meter data. The vibration energy of the vocal folds was determined to be significant up to a frequency of 3 kHz. Three characteristic vibrational waveforms were identified which may indicate bifurcations between vibrational modes of the mucosal wave. No relationship was found between the velocity amplitude and phonation frequency or sound pressure level. A correlation was found between the peak-to-peak displacement amplitude and phonation frequency. A sparse map of the velocity amplitudes on the vocal fold surface was obtained.

SUBMITTER: Chan A

PROVIDER: S-EPMC3606305 | biostudies-other | 2013 Mar

REPOSITORIES: biostudies-other

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Novel Applications of Laser Doppler Vibration Measurements to Medical Imaging.

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Optical measurements of vocal fold tensile properties: implications for phonatory mechanics.

Project description:In voice research, in vitro tensile stretch experiments of vocal fold tissues are commonly employed to determine the tissue biomechanical properties. In the standard stretch-release protocol, tissue deformation is computed from displacements applied to sutures inserted through the thyroid and arytenoid cartilages, with the cartilages assumed to be rigid. Here, a non-contact optical method was employed to determine the actual tissue deformation of vocal fold lamina propria specimens from three excised human larynges in uniaxial tensile tests. Specimen deformation was found to consist not only of deformation of the tissue itself, but also deformation of the cartilages, as well as suture alignment and tightening. Stress-stretch curves of a representative load cycle were characterized by an incompressible Ogden model. The initial longitudinal elastic modulus was found to be considerably higher if determined based on optical displacement measurements than typical values reported in the literature. The present findings could change the understanding of the mechanics underlying vocal fold vibration. Given the high longitudinal elastic modulus the lamina propria appeared to demonstrate a substantial level of anisotropy. Consequently, transverse shear could play a significant role in vocal fold vibration, and fundamental frequencies of phonation should be predicted by beam theories accounting for such effects.

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2014-10-09 | E-GEOD-62204 | biostudies-arrayexpress

Transcription in wounded rat vocal folds and vocal fold fibroblasts

2014-10-09 | GSE62204 | GEO

Influence of subglottic stenosis on the flow-induced vibration of a computational vocal fold model.

Project description:The effect of subglottic stenosis on vocal fold vibration is investigated. An idealized stenosis is defined, parameterized, and incorporated into a two-dimensional, fully-coupled finite element model of the vocal folds and laryngeal airway. Flow-induced responses of the vocal fold model to varying severities of stenosis are compared. The model vibration was not appreciably affected by stenosis severities of up to 60% occlusion. Model vibration was altered by stenosis severities of 90% or greater, evidenced by decreased superior model displacement, glottal width amplitude, and flow rate amplitude. Predictions of vibration frequency and maximum flow declination rate were also altered by high stenosis severities. The observed changes became more pronounced with increasing stenosis severity and inlet pressure, and the trends correlated well with flow resistance calculations. Flow visualization was used to characterize subglottal flow patterns in the space between the stenosis and the vocal folds. Underlying mechanisms for the observed changes, possible implications for human voice production, and suggestions for future work are discussed.

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