A growth arrest-specific (gas) gene codes for a membrane protein.
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ABSTRACT:
SUBMITTER: Manfioletti G
PROVIDER: S-EPMC360655 | biostudies-other | 1990 Jun
REPOSITORIES: biostudies-other
Publications
A growth arrest-specific (gas) gene codes for a membrane protein.
Manfioletti G G Ruaro M E ME Del Sal G G Philipson L L Schneider C C
Molecular and cellular biology 19900601 6
A set of growth arrest-specific (gas) genes whose expression is negatively regulated by serum has recently been identified. We report on the detailed analysis of one of these genes (gas3). The kinetics of regulation by the presence and absence of serum were investigated, and it was found that this gene is regulated at the post-transcriptional level. The encoded protein deduced from the nucleotide sequence showed some similarity to a mitochondrial oxyreductase, and in vitro translation establishe ...[more]
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