Ontology highlight
ABSTRACT:
SUBMITTER: Kawalek A
PROVIDER: S-EPMC3616232 | biostudies-other | 2013 Jan
REPOSITORIES: biostudies-other
Kawałek Adam A Lefevre Sophie D SD Veenhuis Marten M van der Klei Ida J IJ
Aging 20130101 1
We studied the role of peroxisomal catalase in chronological aging of the yeastHansenula polymorpha in relation to various growth substrates. Catalase-deficient (cat) cells showed a similar chronological life span (CLS) relative to the wild-type control upon growth on carbon and nitrogen sources that are not oxidized by peroxisomal enzymes. However, when media contained methylamine, which is oxidized by peroxisomal amine oxidase, the CLS of cat cells was significantly reduced. Conversely, the CL ...[more]