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Rac-(1S,4aS,8aS*)-4a-Hy-droxy-2-methyl-perhydro-spiro-[isoquinoline-4,1'-cyclo-hexa-n]-2'-one.

ABSTRACT: In the title compound, C15H25NO2, all three six-membered rings adopt chair conformations. The cyclo-hexane and piperidine rings within the perhydro-isoquinoline are trans-trans fused. The N atom has a trigonal-pyramidal geometry (the sum of the bond angles is 328.0°). The methyl substituent occupies the sterically preferrable equatorial position. In the crystal, mol-ecules form infinite [100] chains via O-H?N hydrogen bonds.

SUBMITTER: Siaka S

PROVIDER: S-EPMC3647829 | biostudies-other | 2013 May

REPOSITORIES: biostudies-other

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rac-(1S,4aS,8aS*)-4a-Hy-droxy-2-methyl-perhydro-spiro-[isoquinoline-4,1'-cyclo-hexa-n]-2'-one.

Siaka Sorho S Soldatenkov Anatoly T AT Malkova Anastasia V AV Soldatova Svetlana A SA Khrustalev Victor N VN

Acta crystallographica. Section E, Structure reports online 20130405 Pt 5

In the title compound, C15H25NO2, all three six-membered rings adopt chair conformations. The cyclo-hexane and piperidine rings within the perhydro-isoquinoline are trans-trans fused. The N atom has a trigonal-pyramidal geometry (the sum of the bond angles is 328.0°). The methyl substituent occupies the sterically preferrable equatorial position. In the crystal, mol-ecules form infinite [100] chains via O-H⋯N hydrogen bonds. ...[more]

PMID: 23723795

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