Ontology highlight
ABSTRACT:
SUBMITTER: Stiefel KM
PROVIDER: S-EPMC3651468 | biostudies-other | 2013 May
REPOSITORIES: biostudies-other
Stiefel Klaus M KM Englitz Bernhard B Sejnowski Terrence J TJ
Proceedings of the National Academy of Sciences of the United States of America 20130422 19
Cortical spike trains are highly irregular both during ongoing, spontaneous activity and when driven at high firing rates. There is uncertainty about the source of this irregularity, ranging from intrinsic noise sources in neurons to collective effects in large-scale cortical networks. Cortical interneurons display highly irregular spike times (coefficient of variation of the interspike intervals >1) in response to dc-current injection in vitro. This is in marked contrast to cortical pyramidal c ...[more]