Ontology highlight
ABSTRACT:
SUBMITTER: Wilschut KJ
PROVIDER: S-EPMC3659668 | biostudies-other | 2012 Nov
REPOSITORIES: biostudies-other
Wilschut Karlijn J KJ Ling Vivian B VB Bernstein Harold S HS
Stem cells translational medicine 20121023 11
Muscular dystrophy comprises a group of genetic diseases that cause progressive weakness and degeneration of skeletal muscle resulting from defective proteins critical to muscle structure and function. This leads to premature exhaustion of the muscle stem cell pool that maintains muscle integrity during normal use and exercise. Stem cell therapy holds promise as a treatment for muscular dystrophy by providing cells that can both deliver functional muscle proteins and replenish the stem cell pool ...[more]