Ontology highlight
ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC3663895 | biostudies-other | 2013 Apr
REPOSITORIES: biostudies-other
Organic letters 20130327 7
The enantioselective hydroboration of racemic allenylsilane (±)-4 with ((d)Ipc)2BH proceeds via enantiodivergent pathways to give vinylborane 11 and crotylborane intermediate (S)-E-5. Subsequent crotylboration of aldehyde substrates with (S)-E-5 at -78 °C provides (E)-δ-silyl-anti-homoallylic alcohols in 71-89% yield and with 93-96% ee. ...[more]