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The potential harm of oxygen therapy in medical emergencies.


ABSTRACT: In medical emergencies, supplemental oxygen is often administrated routinely. Most paramedics and physicians believe that high concentrations of oxygen are life-saving 1. Over the last century, however, a plethora of studies point to possible detrimental effects of hyperoxia induced by supplemental oxygen in a variety of medical emergencies. This viewpoint provides a historical overview and questions the safety of routine high-dose oxygen administration and is based on pathophysiology and (pre)clinical findings in various medical emergencies.

SUBMITTER: Cornet AD 

PROVIDER: S-EPMC3672526 | biostudies-other | 2013 Apr

REPOSITORIES: biostudies-other

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The potential harm of oxygen therapy in medical emergencies.

Cornet Alexander D AD   Kooter Albertus J AJ   Peters Mike J L MJ   Smulders Yvo M YM  

Critical care (London, England) 20130418 2


In medical emergencies, supplemental oxygen is often administrated routinely. Most paramedics and physicians believe that high concentrations of oxygen are life-saving 1. Over the last century, however, a plethora of studies point to possible detrimental effects of hyperoxia induced by supplemental oxygen in a variety of medical emergencies. This viewpoint provides a historical overview and questions the safety of routine high-dose oxygen administration and is based on pathophysiology and (pre)c  ...[more]

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