Ontology highlight
ABSTRACT:
SUBMITTER: Wu C
PROVIDER: S-EPMC3672883 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Scientific reports 20130101
Although oxygen has been reported to regulate biofilm formation by several Shewanella species, the exact regulatory mechanism mostly remains unclear. Here, we identify a direct oxygen-sensing diguanylate cyclase (DosD) and reveal its regulatory role in biofilm formation by Shewanella putrefaciens CN32 under aerobic conditions. In vitro and in vivo analyses revealed that the activity of DosD culminates to synthesis of cyclic diguanylate (c-di-GMP) in the presence of oxygen. DosD regulates the tra ...[more]