Ontology highlight
ABSTRACT:
SUBMITTER: Burkin HR
PROVIDER: S-EPMC3678871 | biostudies-other | 2013 Jul
REPOSITORIES: biostudies-other
Burkin Heather R HR Rice Monica M Sarathy Apurva A Thompson Sara S Singer Cherie A CA Buxton Iain L O IL
Reproductive sciences (Thousand Oaks, Calif.) 20130108 7
Focal adhesions are integrin-rich microdomains that structurally link the cytoskeleton to the extracellular matrix and transmit mechanical signals. In the pregnant uterus, increases in integrin expression and activation are thought to be critical for the formation of the mechanical syncytium required for labor. The aim of this study was to determine which integrins are upregulated and localized to focal adhesions in pregnant human myometrium. We used quantitative polymerase chain reaction, Weste ...[more]