Dataset Information

Discovering medical conditions associated with periodontitis using linked electronic health records.

ABSTRACT: To use linked electronic medical and dental records to discover associations between periodontitis and medical conditions independent of a priori hypotheses.This case-control study included 2475 patients who underwent dental treatment at the College of Dental Medicine at Columbia University and medical treatment at NewYork-Presbyterian Hospital. Our cases are patients who received periodontal treatment and our controls are patients who received dental maintenance but no periodontal treatment. Chi-square analysis was performed for medical treatment codes and logistic regression was used to adjust for confounders.Our method replicated several important periodontitis associations in a largely Hispanic population, including diabetes mellitus type I (OR = 1.6, 95% CI 1.30-1.99, p < 0.001) and type II (OR = 1.4, 95% CI 1.22-1.67, p < 0.001), hypertension (OR = 1.2, 95% CI 1.10-1.37, p < 0.001), hypercholesterolaemia (OR = 1.2, 95% CI 1.07-1.38, p = 0.004), hyperlipidaemia (OR = 1.2, 95% CI 1.06-1.43, p = 0.008) and conditions pertaining to pregnancy and childbirth (OR = 2.9, 95% CI: 1.32-7.21, p = 0.014). We also found a previously unreported association with benign prostatic hyperplasia (OR = 1.5, 95% CI 1.05-2.10, p = 0.026) after adjusting for age, gender, ethnicity, hypertension, diabetes, obesity, lipid and circulatory system conditions, alcohol and tobacco abuse.This study contributes a high-throughput method for associating periodontitis with systemic diseases using linked electronic records.

SUBMITTER: Boland MR

PROVIDER: S-EPMC3690348 | biostudies-other | 2013 May

REPOSITORIES: biostudies-other

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Discovering medical conditions associated with periodontitis using linked electronic health records.

Boland Mary Regina MR Hripcsak George G Albers David J DJ Wei Ying Y Wilcox Adam B AB Wei Jin J Li Jianhua J Lin Steven S Breene Michael M Myers Ronnie R Zimmerman John J Papapanou Panos N PN Weng Chunhua C

Journal of clinical periodontology 20130315 5

<h4>Aim</h4>To use linked electronic medical and dental records to discover associations between periodontitis and medical conditions independent of a priori hypotheses.<h4>Materials and methods</h4>This case-control study included 2475 patients who underwent dental treatment at the College of Dental Medicine at Columbia University and medical treatment at NewYork-Presbyterian Hospital. Our cases are patients who received periodontal treatment and our controls are patients who received dental ma ...[more]

PMID: 23495669

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Dataset Information

Discovering medical conditions associated with periodontitis using linked electronic health records.

Publications

Discovering medical conditions associated with periodontitis using linked electronic health records.

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