Ontology highlight
ABSTRACT:
SUBMITTER: Akhtar MM
PROVIDER: S-EPMC3711888 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Akhtar Most Mauluda MM Scala Giovanni G Cocozza Sergio S Miele Gennaro G Monticelli Antonella A
BMC evolutionary biology 20130710
<h4>Background</h4>Histone modification is an epigenetic mechanism that influences gene regulation in eukaryotes. In particular, histone modifications in CpG islands (CGIs) are associated with different chromatin states and with transcription activity. Changes in gene expression play a crucial role in adaptation and evolution.<h4>Results</h4>In this paper, we have studied, using a computational biology approach, the relationship between histone modifications in CGIs and selective pressure in Hom ...[more]