Ontology highlight
ABSTRACT:
SUBMITTER: Santos JR
PROVIDER: S-EPMC3724821 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Santos José R JR Muñoz-Moreno José A JA Moltó José J Prats Anna A Curran Adrià A Domingo Pere P Llibre Josep M JM McClernon Daniel R DR Bravo Isabel I Canet Jaume J Watson Victoria V Back David D Clotet Bonaventura B
PloS one 20130726 7
<h4>Background</h4>Data on suppression of HIV replication in the CNS and on the subsequent risk of neurocognitive impairment using monotherapy with boosted protease inhibitors are limited.<h4>Methods</h4>Ours was an exploratory cross-sectional study in patients on lopinavir/ritonavir-based monotherapy (LPV/r-MT) or standard triple therapy (LPV/r-ART) for at least 96 weeks who maintained a plasma viral load <50 copies/mL. HIV-1 RNA in CSF was determined by HIV-1 SuperLow assay (lower limit of det ...[more]