Ontology highlight
ABSTRACT:
SUBMITTER: Morrissey RP
PROVIDER: S-EPMC3734744 | biostudies-other | 2011 Jan-Feb
REPOSITORIES: biostudies-other
Morrissey R P RP Philip K J KJ Schwarz E R ER
Cardiovascular journal of Africa 20110101 1
Fabry's disease is an X-linked lysosomal storage disease most often associated with renal dysfunction and death due to renal failure in patients' fourth and fifth decades of life. However, cardiac manifestations including arrhythmias, angina and heart failure are common and probably underrecognized. Furthermore, Fabry's disease is now recognised as also affecting female carriers, who manifest signs later than males. A variant of Fabry's has been identified that only affects cardiac tissue, which ...[more]