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Protein adsorption enhanced radio-frequency heating of silica nanoparticles.


ABSTRACT: Measurements of specific-absorption-rate (SAR) of silica 30, 50, and 100 nm nanoparticles (NP) suspended in water were carried out at 30 MHz in 7 kV/m radio-frequency (rf) electric field. Size dependent, NP-suspension interface related heating of silica NP was observed. To investigate a possible mechanism of heating, bovine serum albumin was adsorbed on the surface of silica NPs in suspension. It resulted in significant enhancement of SAR when compared to bare silica NPs. A calorimetric and rf loss model was used to calculate effective conductivity of silica NP with/without adsorbed albumin as a function of silica size and albumin concentration.

SUBMITTER: Wosik J 

PROVIDER: S-EPMC3739802 | biostudies-other | 2013 Jul

REPOSITORIES: biostudies-other

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