Ontology highlight
ABSTRACT:
SUBMITTER: Turner AR
PROVIDER: S-EPMC3753782 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Turner A R AR Kader A K AK Xu J J
Journal of internal medicine 20120401 4
Genome-wide association studies have identified thousands of consistently replicated associations between genetic markers and complex disease risk, including cancers. Alone, these markers have limited utility in risk prediction; however, when several of these markers are used in combination, the predictive performance appears to be similar to that of many currently available clinical predictors. Despite this, there are divergent views regarding the clinical validity and utility of these genetic ...[more]