Ontology highlight
ABSTRACT:
SUBMITTER: Armaganijan L
PROVIDER: S-EPMC3763643 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Armaganijan Luciana L Patel Dimpi D Dietrich Cristiano C Morillo Carlos A CA
Pharmaceuticals (Basel, Switzerland) 20120405 4
Atrial Fibrillation (AF) is the most common sustained arrhythmia and 1/6 strokes is attributed to AF. The cornerstone of treatment remains maintaining sinus rhythm or appropriate ventricular rate control in addition to prevention of stroke. Oral anticoagulation therapy (OAC) with vitamin K antagonists (VKAs) has been the gold standard for almost 50 years and a significant reduction in the risk of stroke in patients with AF has been demonstrated. Nonetheless, only 50% of patients with guideline r ...[more]