Unknown

Dataset Information

0

Multi-MHz retinal OCT.


ABSTRACT: We analyze the benefits and problems of in vivo optical coherence tomography (OCT) imaging of the human retina at A-scan rates in excess of 1 MHz, using a 1050 nm Fourier-domain mode-locked (FDML) laser. Different scanning strategies enabled by MHz OCT line rates are investigated, and a simple multi-volume data processing approach is presented. In-vivo OCT of the human ocular fundus is performed at different axial scan rates of up to 6.7 MHz. High quality non-mydriatic retinal imaging over an ultra-wide field is achieved by a combination of several key improvements compared to previous setups. For the FDML laser, long coherence lengths and 72 nm wavelength tuning range are achieved using a chirped fiber Bragg grating in a laser cavity at 419.1 kHz fundamental tuning rate. Very large data sets can be acquired with sustained data transfer from the data acquisition card to host computer memory, enabling high-quality averaging of many frames and of multiple aligned data sets. Three imaging modes are investigated: Alignment and averaging of 24 data sets at 1.68 MHz axial line rate, ultra-dense transverse sampling at 3.35 MHz line rate, and dual-beam imaging with two laser spots on the retina at an effective line rate of 6.7 MHz.

SUBMITTER: Klein T 

PROVIDER: S-EPMC3799654 | biostudies-other | 2013

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC4467705 | biostudies-literature
| S-EPMC6438632 | biostudies-literature
| S-EPMC2734481 | biostudies-literature
| S-EPMC6603187 | biostudies-literature
| S-EPMC4108297 | biostudies-literature
| S-EPMC6492610 | biostudies-literature
| S-EPMC7484327 | biostudies-literature
| S-EPMC8386161 | biostudies-literature
| S-EPMC6887517 | biostudies-literature
| S-EPMC5932624 | biostudies-literature