Ontology highlight
ABSTRACT:
SUBMITTER: Stock DW
PROVIDER: S-EPMC38247 | biostudies-other | 1996 Oct
REPOSITORIES: biostudies-other
Stock D W DW Ellies D L DL Zhao Z Z Ekker M M Ruddle F H FH Weiss K M KM
Proceedings of the National Academy of Sciences of the United States of America 19961001 20
The vertebrate Dlx gene family consists of homeobox-containing transcription factors distributed in pairs on the same chromosomes as the Hox genes. To investigate the evolutionary history of Dlx genes, we have cloned five new zebrafish family members and have provided additional sequence information for two mouse genes. Phylogenetic analyses of Dlx gene sequences considered in the context of their chromosomal arrangements suggest that an initial tandem duplication produced a linked pair of Dlx g ...[more]