Ontology highlight
ABSTRACT:
SUBMITTER: Shimamoto A
PROVIDER: S-EPMC38257 | biostudies-other | 1996 Oct
REPOSITORIES: biostudies-other
Shimamoto A A Kitao S S Ichikawa K K Suzuki N N Yamabe Y Y Imamura O O Tokutake Y Y Satoh M M Matsumoto T T Kuromitsu J J Kataoka H H Sugawara K K Sugawara M M Sugimoto M M Goto M M Furuichi Y Y
Proceedings of the National Academy of Sciences of the United States of America 19961001 20
A unique gene, RBP-MS, spanning over 230 kb in the human chromosome 8p11-12 near the Werner syndrome gene locus is described. The single-copy RBP-MS gene is alternatively spliced, resulting in a family of at least 12 transcripts (average length of 1.5 kb). Nine different types of cDNAs that encode an RNa-binding motif at the N terminus and helix-rich sequences at the C terminus have been identified thus far. Among the 16 exons identified, four 5'-proximal exons contained sequences homologous to ...[more]