Ontology highlight
ABSTRACT:
SUBMITTER: Micoli F
PROVIDER: S-EPMC3839747 | biostudies-other | 2013 Nov
REPOSITORIES: biostudies-other
Micoli Francesca F Romano Maria Rosaria MR Tontini Marta M Cappelletti Emilia E Gavini Massimiliano M Proietti Daniela D Rondini Simona S Swennen Erwin E Santini Laura L Filippini Sara S Balocchi Cristiana C Adamo Roberto R Pluschke Gerd G Norheim Gunnstein G Pollard Andrew A Saul Allan A Rappuoli Rino R MacLennan Calman A CA Berti Francesco F Costantino Paolo P
Proceedings of the National Academy of Sciences of the United States of America 20131104 47
Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the African meningitis belt, and has a high associated mortality. The meningococcal serogroups A, W, and X have been responsible for epidemics and almost all cases of meningococcal meningitis in the meningitis belt over the past 12 y. Currently no vaccine is available against meningococcal X (MenX). Because the development of a new vaccine through to licensure takes many years, this leaves Africa vulnerable ...[more]