Ontology highlight
ABSTRACT:
SUBMITTER: Thomassen YE
PROVIDER: S-EPMC3861478 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Thomassen Yvonne E YE van 't Oever Aart G AG van Oijen Monique G C T MG Wijffels René H RH van der Pol Leo A LA Bakker Wilfried A M WA
PloS one 20131212 12
Worldwide efforts to eradicate polio caused a tipping point in polio vaccination strategies. A switch from the oral polio vaccine, which can cause circulating and virulent vaccine derived polioviruses, to inactivated polio vaccines (IPV) is scheduled. Moreover, a manufacturing process, using attenuated virus strains instead of wild-type polioviruses, is demanded to enhance worldwide production of IPV, especially in low- and middle income countries. Therefore, development of an IPV from attenuate ...[more]