Unknown

Dataset Information

0

Functional heterogeneity in posterior parietal cortex across attention and episodic memory retrieval.


ABSTRACT: While attention is critical for event memory, debate has arisen regarding the extent to which posterior parietal cortex (PPC) activation during episodic retrieval reflects engagement of PPC-mediated mechanisms of attention. Here, we directly examined the relationship between attention and memory, within and across subjects, using functional magnetic resonance imaging attention-mapping and episodic retrieval paradigms. During retrieval, 4 functionally dissociable PPC regions were identified. Specifically, 2 PPC regions positively tracked retrieval outcomes: lateral intraparietal sulcus (latIPS) indexed graded item memory strength, whereas angular gyrus (AnG) tracked recollection. By contrast, 2 other PPC regions demonstrated nonmonotonic relationships with retrieval: superior parietal lobule (SPL) tracked retrieval reaction time, consistent with a graded engagement of top-down attention, whereas temporoparietal junction displayed a complex pattern of below-baseline retrieval activity, perhaps reflecting disengagement of bottom-up attention. Analyses of retrieval effects in PPC topographic spatial attention maps (IPS0-IPS5; SPL1) revealed that IPS5 and SPL1 exhibited a nonmonotonic relationship with retrieval outcomes resembling that in the SPL region, further suggesting that SPL activation during retrieval reflects top-down attention. While demands on PPC attention mechanisms vary during retrieval attempts, the present functional parcellation of PPC indicates that 2 additional mechanisms (mediated by latIPS and AnG) positively track retrieval outcomes.

SUBMITTER: Hutchinson JB 

PROVIDER: S-EPMC3862264 | biostudies-other | 2014 Jan

REPOSITORIES: biostudies-other

altmetric image

Publications

Functional heterogeneity in posterior parietal cortex across attention and episodic memory retrieval.

Hutchinson J Benjamin JB   Uncapher Melina R MR   Weiner Kevin S KS   Bressler David W DW   Silver Michael A MA   Preston Alison R AR   Wagner Anthony D AD  

Cerebral cortex (New York, N.Y. : 1991) 20120926 1


While attention is critical for event memory, debate has arisen regarding the extent to which posterior parietal cortex (PPC) activation during episodic retrieval reflects engagement of PPC-mediated mechanisms of attention. Here, we directly examined the relationship between attention and memory, within and across subjects, using functional magnetic resonance imaging attention-mapping and episodic retrieval paradigms. During retrieval, 4 functionally dissociable PPC regions were identified. Spec  ...[more]

Similar Datasets

| S-EPMC3098040 | biostudies-literature
| S-EPMC3339571 | biostudies-literature
| S-EPMC2906749 | biostudies-literature
| S-EPMC7542540 | biostudies-literature
| S-EPMC5907360 | biostudies-literature
| S-EPMC5015486 | biostudies-literature
| S-EPMC2778240 | biostudies-literature
| S-EPMC2790392 | biostudies-literature
| S-EPMC5390398 | biostudies-literature
| S-EPMC3844282 | biostudies-literature