Real-world impact of education: treating patients with ipilimumab in a community practice setting.
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ABSTRACT:
SUBMITTER: Ledezma B
PROVIDER: S-EPMC3873235 | biostudies-other | 2013 Dec
REPOSITORIES: biostudies-other
Publications
Real-world impact of education: treating patients with ipilimumab in a community practice setting.
Cancer management and research 20131221
After decades without promising new treatments for advanced and metastatic melanoma, ipilimumab was the first systemic therapy approved for use in this patient population. A fully human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen 4 (CTLA-4) to augment antitumor T-cell responses, ipilimumab significantly extended overall survival in clinical trials. Because ipilimumab is associated with a set of immune-related adverse events that likely reflect the agent's mechanism of action, ...[more]
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