Ontology highlight
ABSTRACT:
SUBMITTER: Lujan HD
PROVIDER: S-EPMC38797 | biostudies-other | 1996 Jul
REPOSITORIES: biostudies-other
Luján H D HD Mowatt M R MR Byrd L G LG Nash T E TE
Proceedings of the National Academy of Sciences of the United States of America 19960701 15
Giardia lamblia, like most human intestinal parasitic protozoa, sustains fundamental morphological and biochemical changes to survive outside the small intestine of its mammalian host by differentiating into an infective cyst. However, the stimulus that triggers this differentiation remains totally undefined. In this work, we demonstrate the induction of cyst formation in vitro when trophozoites are starved for cholesterol. Expression of cyst wall proteins was detected within encystation-specifi ...[more]