Ontology highlight
ABSTRACT:
SUBMITTER: Bullwinkle TJ
PROVIDER: S-EPMC3883804 | biostudies-other | 2014
REPOSITORIES: biostudies-other
The aminoacyl-tRNA synthetases (aaRSs) are essential components of the protein synthesis machinery responsible for defining the genetic code by pairing the correct amino acids to their cognate tRNAs. The aaRSs are an ancient enzyme family believed to have origins that may predate the last common ancestor and as such they provide insights into the evolution and development of the extant genetic code. Although the aaRSs have long been viewed as a highly conserved group of enzymes, findings within ...[more]