Critical slowing down as early warning for the onset and termination of depression.
Ontology highlight
ABSTRACT:
SUBMITTER: van de Leemput IA
PROVIDER: S-EPMC3890822 | biostudies-other | 2014 Jan
REPOSITORIES: biostudies-other
Publications
Critical slowing down as early warning for the onset and termination of depression.
van de Leemput Ingrid A IA Wichers Marieke M Cramer Angélique O J AO Borsboom Denny D Tuerlinckx Francis F Kuppens Peter P van Nes Egbert H EH Viechtbauer Wolfgang W Giltay Erik J EJ Aggen Steven H SH Derom Catherine C Jacobs Nele N Kendler Kenneth S KS van der Maas Han L J HL Neale Michael C MC Peeters Frenk F Thiery Evert E Zachar Peter P Scheffer Marten M
Proceedings of the National Academy of Sciences of the United States of America 20131209 1
About 17% of humanity goes through an episode of major depression at some point in their lifetime. Despite the enormous societal costs of this incapacitating disorder, it is largely unknown how the likelihood of falling into a depressive episode can be assessed. Here, we show for a large group of healthy individuals and patients that the probability of an upcoming shift between a depressed and a normal state is related to elevated temporal autocorrelation, variance, and correlation between emoti ...[more]
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