Ontology highlight
ABSTRACT:
SUBMITTER: Dunn FA
PROVIDER: S-EPMC3894852 | biostudies-other | 2013 Dec
REPOSITORIES: biostudies-other
Neuron 20131201 5
Specific connectivity patterns among neurons create the basic architecture underlying parallel processing in our nervous system. Here we focus on the visual system's first synapse to examine the structural and functional consequences of sensory deprivation on the establishment of parallel circuits. Dark rearing reduces synaptic strength between cones and cone bipolar cells, a previously unappreciated effect of sensory deprivation. In contrast, rod bipolar cells, which utilize the same glutamate ...[more]