Ontology highlight
ABSTRACT:
SUBMITTER: Peters JP
PROVIDER: S-EPMC3905893 | biostudies-other | 2013 Dec
REPOSITORIES: biostudies-other
Peters Justin P JP Yelgaonkar Shweta P SP Srivatsan Seergazhi G SG Tor Yitzhak Y James Maher L L
Nucleic acids research 20130905 22
The molecular structure of the DNA double helix has been known for 60 years, but we remain surprisingly ignorant of the balance of forces that determine its mechanical properties. The DNA double helix is among the stiffest of all biopolymers, but neither theory nor experiment has provided a coherent understanding of the relative roles of attractive base stacking forces and repulsive electrostatic forces creating this stiffness. To gain insight, we have created a family of double-helical DNA-like ...[more]