Ontology highlight
ABSTRACT:
SUBMITTER: Davies M
PROVIDER: S-EPMC3917949 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Cancer management and research 20140203
Recent advances in the understanding of immunology and antitumor immune responses have led to the development of new immunotherapies, including vaccination approaches and monoclonal antibodies that inhibit immune checkpoint pathways. These strategies have shown activity in melanoma and are now being tested in lung cancer. The antibody drugs targeting cytotoxic T-lymphocyte-associated antigen-4 and programmed cell death protein-1 immune checkpoint pathways work by restoring immune responses again ...[more]