Ontology highlight
ABSTRACT:
SUBMITTER: Allen LA
PROVIDER: S-EPMC3961583 | biostudies-other | 2009 Jun
REPOSITORIES: biostudies-other
Allen Larry A LA Hernandez Adrian F AF O'Connor Christopher M CM Felker G Michael GM
Journal of the American College of Cardiology 20090601 24
Acute heart failure syndromes (AHFS) remain a major cause of morbidity and mortality, in part because the development of new therapies for these disorders has been marked by frequent failure and little success. The heterogeneity of current approaches to AHFS drug development, particularly with regard to end points, remains a major potential barrier to progress in the field. End points involving hemodynamic status, biomarkers, symptoms, hospital stay, end organ function, and mortality have all be ...[more]