Ontology highlight
ABSTRACT:
SUBMITTER: Longbrake EE
PROVIDER: S-EPMC3967547 | biostudies-other | 2013 Nov
REPOSITORIES: biostudies-other
Longbrake Erin E EE Parks Becky J BJ Cross Anne H AH
Current neurology and neuroscience reports 20131101 11
Multiple sclerosis (MS), a demyelinating disease of the central nervous system, was untreatable until the mid-1990s when beta-interferons and glatiramer acetate were introduced. These agents, while effective, were relatively nonspecific in action. Over the last 10 years, research has focused toward developing more targeted therapies for the disease. Monoclonal antibodies (mAbs) have been central to these efforts and many of the mAbs studied in MS have been singularly effective. We review here th ...[more]