Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.
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ABSTRACT:
SUBMITTER: Haynes HR
PROVIDER: S-EPMC3970023 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Publications
Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.
Haynes Harry R HR Camelo-Piragua Sandra S Kurian Kathreena M KM
Frontiers in oncology 20140324
It is increasingly clear that both adult and pediatric glial tumor entities represent collections of neoplastic lesions, each with individual pathological molecular events and treatment responses. In this review, we discuss the current prognostic biomarkers validated for clinical use or with future clinical validity for gliomas. Accurate prognostication is crucial for managing patients as treatments may be associated with high morbidity and the benefits of high risk interventions must be judged ...[more]
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