Ontology highlight
ABSTRACT:
SUBMITTER: Conway O'Brien E
PROVIDER: S-EPMC3980839 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Conway O'Brien Emma E Prideaux Steven S Chevassut Timothy T
Advances in hematology 20140323
Acute myeloid leukemia (AML) is a genetically heterogeneous disease. Certain cytogenetic and molecular genetic mutations are recognized to have an impact on prognosis, leading to their inclusion in some prognostic stratification systems. Recently, the advent of high-throughput whole genome or exome sequencing has led to the identification of several novel recurrent mutations in AML, a number of which have been found to involve genes concerned with epigenetic regulation. These genes include in pa ...[more]